MitoWorld™ is a web platform, or portal, that brings together the latest research and emerging fields associated with mitochondrial research, patient support, health resources, and the growing understanding of the importance of healthy energy production in medicine and health. [More]
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Mitochondrial Transport of Methylated Amino Acids
A multi-institute research group led by Thomas MacVicar at the Cancer Research UK Scotland Institute, Glasgow, found that a specific transporter called SLC25A45 is required for the transport of methylated amino acids across the inner mitochondrial membrane and for carnitine…Read more…
Mitochondrial Dynamics and T-Cell Activation
The activation of T cells is a critical part of our adaptive immune system. T-cell activation requires massive increases in gene expression and cell proliferation, which is dependent on increased energy production. A research team at the Cancer Research UK…Read more…
Mitochondrial Transfer and Lymph Node Metastasis
The immune system is our first line of defense against cancer. However, tumors have developed mechanisms to evade the immune system and even to invade tumor strongholds, such as lymph nodes. A multi-institute research team led by Azusa Terasaki and…Read more…
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MitoCast
Chris Mason and Afshin Beheshti: Is Life in Space Possible?
Chris Mason (WorldQuant Professor at Weill Cornell Medicine) and Afshin Beheshti (Director of Center for Space Biomedicine, Associate Director of McGowan Institute for Regenerative Medicine, and Professor of Surgery and Computational and Systems Biology at University of Pittsburgh) are top…Read more…
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Latest Research
- The genome sequence of the Pink Pigeon, Nesoenas mayeri (Prévost, 1843)
- The genome sequence of a cased caddisfly, Ceraclea dissimilis (Stephens, 1836)
- Pathological PNPase variants with altered RNA binding and degradation activity affect the phenotype of bacterial and human cell models
- Nuclear transfer leads to aberrant cell cycle regulation and translation, as determined by gene expression, and selection of mitochondrial DNA in porcine blastocysts
- Correction to 'Nuclear transfer leads to aberrant cell cycle regulation and translation, as determined by gene expression, and selection of mitochondrial DNA in porcine blastocysts'
- The complete mitochondrial genome Hainan Gymnure, Neohylomys hainanensis
- The genome sequence of the European shag, Gulosus aristotelis (previously Phalacrocorax aristotelis) (Linnaeus, 1761)
- The genome sequence of the Greater Wax Moth, Galleria mellonella (Linnaeus, 1758)
- The genome sequence of the lesser black-backed gull, Larus fuscus Linnaeus, 1758
- The genome sequence of Trimmer's Mining Bee, Andrena trimmerana (Kirby, 1802)
- The genome sequence of the March moth, Alsophila aescularia (Denis & Schiffermüller)
- Model systems informing mechanisms and drug discovery: a review of POLG-related disease models
- Structural insights into cauliflower mitoribosome in translation state and in association with a late assembly factor
- Ei24 deficiency in brown adipocytes induces severe hypothermia under cold stress independent of UCP1 activity
- Sprint interval exercise disrupts mitochondrial ultrastructure driving a unique mitochondrial stress response and remodelling in men
- NEK7 couples SDHB to orchestrate respiratory chain electron transport homeostasis that impedes liver fibrosis
- Mechanical confinement induces ferroptosis through mitochondrial dysfunction
- Acetyl-CoA carboxylase maintains energetic balance for functional oogenesis
- N-terminal α-amino SUMOylation promotes phosphorylation-independent cofilin-1 translocation to the mitochondrial matrix and induces apoptosis
- Microprotein PLUM encoded by Lin28b uORF is a cytoplasmic determinant of pluripotency and embryonic development
- Toxoplasma effector TgROP1 establishes membrane contact sites with the endoplasmic reticulum during infection
- The S-depalmitoylase ABHD10 is essential for sperm mitochondrial sheath formation and male fertility
- Investigation of mitochondrial phenotypes in motor neurons derived by direct conversion of fibroblasts from familial ALS subjects
- An inherited mitochondrial DNA mutation remodels inflammatory cytokine responses in macrophages and in vivo in mice