About
We are an interdisciplinary team of scientists driven to understand the biochemical underpinnings of mitochondrial dysfunction in human diseases. Together, we integrate large-scale methodologies with traditional biochemistry to investigate the modulation, adaptation, and basic metabolic function of mitochondria.
On the web
Website: https://pagliarinilab.org/
People
David J. Pagliarini, PhD
Hugo F. & Ina C. Urbauer Professor and BJC Investigator Departments of Cell Biology & Physiology, Biochemistry and Molecular Biophysics, and Genetics
Bio
Dave Pagliarini is a BJC Investigator and the Hugo F. and Ina C. Urbauer Professor of Cell Biology & Physiology, Biochemistry & Molecular Biophysics, and Genetics at Washington University School of Medicine in St. Louis, and is a member of the McDonnell Genome Institute Leadership Council. After graduating with honors in biochemistry from the University of Notre Dame in 1999, Dave conducted his graduate training with Michael Marletta and Jack Dixon, receiving his Ph.D. in biochemistry from UC San Diego in 2005. For his postdoctoral work, Dave joined Vamsi Mootha’s group at Harvard Medical School/The Broad Institute, where he led an integrative systems biology effort to define mammalian mitochondrial protein composition and function (the MitoCarta project). Dave joined the faculty of the University of Wisconsin–Madison in the Department of Biochemistry in 2009, where he was promoted to Associate Professor in 2015 and full Professor in 2020. In 2015, Dave also became the Lead Investigator and Arthur C. Nielsen Jr. Chair of Metabolism at the Morgridge Institute for Research, where he led a campus-wide initiative to enhance metabolism-related research in Madison. In 2020, Dave was named the fifth ‘BJC Investigator’ at Washington University. He lives in St. Louis with his wife, Carrie, and their two sons.
On The Web
David's profile at his lab: https://pagliarinilab.org/dave-pagliarini%20