Beyond The Disease, March 3, 2026

Keystone Symposia’s Mitochondria Signaling in Physiology and Disease: If you missed the Keystone Symposia conference Mitochondria Signaling in Physiology and Disease—held February 9–12, 2026 at Keystone Resort in Colorado—you now have a second chance. On Demand registration is open, giving you access to the full main-session program from one of the most significant gatherings in mitochondrial biology in recent years.

In a recent paper in Molecular Cell, a multi-institute research group led by Thomas MacVicar at the Cancer Research UK Scotland Institute, Glasgow, studied transporter proteins that move cargos across the mitochondrial inner membrane. They found that a specific transporter called SLC25A45 is required for the transport of methylated amino acids and carnitine synthesis.

In a recent paper in Cell Reports, a research team at the Cancer Research UK Scotland Institute in Glasgow, led by Alison Galloway, Victoria H. Cowling and Tom MacVicar, examined the mechanisms regulating T-cell activation. Mitochondria act as a signaling nexus in T-cells, and they found that that the energetic capacity of T cells is regulated by alternative splicing of proteins involved in mitochondrial fission and fusion during activation.

A recent paper in Cell Metabolism describes a multi-institute study led by Azusa Terasaki and Derick Okwan-Duodu of Stanford University. The team explore the mechanisms that tumor cells use to defeat our immune system. They discovered that cancer cells kidnap mitochondria from immune cells. This action weakens the ability of the immune cells to defend against the tumor cells and allows the tumor to invade lymph nodes.