MitoWorld

In “Beyond the Disease” MitoWorld partners with the United Mitochondrial Disease Foundation (UMDF) to highlight advances in mitochondrial science and the people responsible for them. www.MitoWorld.org is devoted to better public and medical understanding of underlying mitochondrial science in an effort to raise awareness of the field in order to attract greater funding for the pursuit of mitochondrial disease and dysfunction.

Mitochondrial Medicine 2025, St. Louis, USA

In an Interview with Johnatan Brestoff, MitoWorld organizer Gordon Freedman, queries Jonathan Brestoff, MD, PhD, MPH, associate professor of pathology & immunology at Washington University School of Medicine in St. Louis. We asked Dr. Brestoff to explain his work and what is being organized from the Scientific and Medical Community session at UMDF (United Mitochondrial Disease Foundation).

Microscopy showing mitochondrial networks in cells

In Innate Immune System Dysfunction in Mitochondrial Diseases, MitoWorld editor Gary Howard summarizes a new paper from Dr. Philip West at The Jackson Laboratory and published in Nature Communication. The paper describes hyperactivity of the innate immune system in a model of mitochondrial disease and identifies potential therapeutic targets for those diseases.

Abstract depiction of a red and blue electric mitochondria surrounded by a bone and various organs of the human body

In Mitochondrial Disease and Endocrine Function, MitoWorld editor Gary Howard summarizes a new paper from Drs. Rachel Varughese and Shamima Rahman of University College London and published in Endocrine Reviews. The paper describes the effects of primary mitochondrial disease on the endocrine system and how these diseases can be diagnosed and treated.

Cover of the Cell Science Special Issue on Mitochondria

In a Special Issue: Cell Biology of Mitochondria, MitoWorld organizer Gordon Freedman summaries the masterful compendium of articles, papers, reviews, interviews and opinion pieces just released in The Journal of Cell Science: Cell Biology of Mitochondria. There is reading here for weeks in the most comprehensive view of the rising field of mitochondria biology aimed at understanding dynamics, basic science, health and disease from the leading researchers globally.

In Mitochondria Are More Than Powerhouses—They’re the Motherboard of the Cell, MitoWorld organizer Gordon Freedman, reports on the Scientific American mitochondria article online authored by Columbia’s Martin Picard, PhD. Dr. Picard posits the communal nature of mitochondria and their analogy to microprocessors. In July 1957, Scientific American published the now-famous “Powerhouse of the Cell” article branding mitochondria for decades to come.

Beyond The Disease, May 31, 2025