The Madrid-based Lab of José Antonio Enríquez, PhD, is dedicated to understanding mitochondrial respiration from the point of view of evolution and basic science. In this special feature, lab member Michael Veliova portrays the lab and interviews it leader while MitoWorld’s Dane Wolf exams the labs latest work.
Mitochondria, Curiosity, and Crazy Ideas: Inside Dr. Toño Enríquez’s GenOXPHOS Lab
Dr. José Antonio Enríquez—known to his lab simply as Toño—leads the Functional Genetics of the Oxidative Phosphorylation System (GenOXPHOS) group at the Spanish National Centre for Cardiovascular Research (CNIC). Using large-scale bioinformatics, his lab investigates many aspects of mitochondria, including…Read more…
MitoWorld had a few questions for Dr. Enríquez and his Lab
MitoWorld: The text notes that you enjoy thinking about “crazy” ideas. What is the “craziest” idea that intrigues you now? One idea I’ve had for years is to replace the electron transport chain, complex I, III, and IV, for only two…Read more…
How Evolution Shapes the OxPhos Machinery: New Insights from Structural and Genomic Analysis
Preface: If we consider that mitochondria are the power plants of the cell, it may come as no surprise that they house a complex array of molecular machines, fine-tuned to churn out copious amounts of energy. What is remarkable, however,…Read more…